Skip to content
Create account to build your panelHelp me choose

Lab Tests to Consider Before Starting Birth Control

By the EllaDx team · Updated November 30, 2025 · 1 min read

For education only, not a diagnosis. Talk to your clinician about your results.

← Back to Journal

Hormonal birth control is safe for most women, but certain pre-existing conditions affect which options are appropriate. Testing can help personalize your choice.

Why Test Before Birth Control?

Birth control can:

  • Affect blood clot risk
  • Deplete certain nutrients
  • Mask underlying conditions
  • Impact future fertility assessment

Recommended Tests

Blood Clot Risk

  • Factor V Leiden (genetic clotting disorder)
  • Prothrombin gene mutation
  • If personal or family history of clots

Baseline Hormones (Optional)

  • FSH, LH, Estradiol
  • Testosterone
  • These establish your baseline before suppression

Nutrient Levels

Birth control can deplete:

  • B vitamins (especially B6, B12, folate)
  • Magnesium
  • Zinc
  • Vitamin C

Thyroid

  • TSH at minimum
  • Full panel if symptoms present

Metabolic

  • Fasting glucose
  • Lipid panel

Why This Matters

Establishing baselines before starting birth control:

  • Identifies pre-existing conditions
  • Helps monitor for changes
  • Provides data for future fertility planning
  • Guides nutrient supplementation

Special Considerations

Certain conditions affect birth control choice:

  • Migraines with aura
  • History of blood clots
  • Certain heart conditions
  • Active liver disease
  • Breast cancer history

References

  • Curtis, K. M., et al. (2016). U.S. medical eligibility criteria for contraceptive use, 2016. MMWR Recommendations and Reports, 65(3), 1-103.
  • Palmery, M., et al. (2013). Oral contraceptives and changes in nutritional requirements. European Review for Medical and Pharmacological Sciences, 17(13), 1804-1813.